3rd International Symposium on Animal Functional Genomics (ISAFG)

Complex Genetic Control of Susceptibility to Malaria: Lessons from the Mouse - Professor Philippe Gros (McGill University)

Session 1:  “Genetics and QTLs”
Chairperson: Dr DJ DeKoning (Roslin Institute) & Dr Luc Janss (DIAS/University of Arhus, Denmark)

• Development and Applications of a Bovine 50,000 SNP Chip - Prof Jerry Taylor (University of Missouri, USA)
• Sex, breeds,... and microarrays - Dr Miguel Perez – Enciso (University of Barcelona, Spain)

Session 2: “Bioinformatics & Data Mining”
Chairperson:  Dr Jan Aerts (Roslin Institute) & Dr Guilherme Rosa (University of Wisconsin, Madison, USA)

• A Transcriptional Connectivity Map for Biomedical Discovery - Dr Justin Lamb (Broad Institute, USA)
• Network Reconstruction through Data Integration - Dr Hongyu Zhao (Yale University, USA)

Eurofins MWG-Operon Company Presentation

Ultra-Highthroughput Sequencing with the Roche Genome Sequencer FLX – Technology, Applications and Software Solutions
Dr Georg Gradl (Eurofins MWG GmbH, Ebersberg, Germany)

Session 3: “Animal Health”
Chairperson: Dr Kirsty Jensen (Roslin Institute) & Dr Marie-Hélène Pinard-van der Laan (INRA/EADGENE coordinator, France)

• Applied Bovine Genomics: Chipping Away at the Genetics Underlying Disease Traits - Tad S Sonstegard (USDA, USA)
• Dr Rachel Rupp (IRNA, France)

Session 4: “Functional Genomics meets Physiology I”  Chairperson: Prof John Mullins (Centre for Cardiovascular Science, University of Edinburgh)& Dr David McHugh (University College Dublin, Ireland)

• Exercise-induced gene expression in equine skeletal muscle - Dr Emmeline Hill (University College Dublin, Ireland)
• The Complex Nature of QTLS: How Many Genes are Under the Peak? - Professor Howard Jacob (Medical College of Wisconsin, USA)

Company Presentation

Animal Functional Genomics using the MaasARRAY®System
Dr Robin Everts, Sequenom, USA

Session 5: “Functional Genomics meets Physiology II”
Chairperson: Dr Tony Reverter (CSRIO, Australia) & Dr Luis Furlan (Sao Paulo State University, Brazil)

• Genomic Approaches to the Reproductive Physiology of the Postpartum Cow - Dr Sigrid Lehnert (CSIRO Livestock Industries, Australia)
• A Systems Biology View of Muscle Development - Dr Brian P. Dalrymple (Computational and Systems Biology CSIRO Livestock Industries, Australia)

Parallel Sessions

16.00 – 18.00 - “Creating, sharing and using biological pathways using WikiPathways, PathVisio and GenMAPP” Thomas Kelder and Martijn van Iersel (University of Maastricht, The Netherlands)

16.00 – 18.00 - “GO Annotations training session” Fiona McCarthy (The AgBase Databases, Mississippi State University, USA)

16.00 – 16.30 - Applied Biosystems - 30 minute demonstration/equipment tutorial

Fast and Reliable High Throughput DNA Analysis Using Taqman® SNP Genotyping Assays and the Biotrove™ Open Array System Phoebe White (Director Genotyping Applications Applied Biosystems, Foster City, US)

Other parallel sessions to be announced

Session 6: “Proteomics”
Chairperson: Dr David Smith (Moredun, Scotland) & Prof Rob Beynon (University of Liverpool, UK)

• Proteome Studies of Host-microbiome Interactions - Dr Emøke Bendixen (Danish Institute of Agricultural Sciences (DIAS), Denmark)
• Deriving Biological Meaning for Patchy Proteomics - Dr Shane C Burgess (Mississippi State University, USA)

Session 7: “Open Session 1”
Chairs: Richard Talbot (ARK-Genomics) and Dr Guilherme Rosa (University of Wisconsin, USA)

10.30 - 10.45 - O1 - Inference on Hidden Population Substructure and Genetic Background of Cattle from Dense SNP Genotype Data -
E Chan, A Reverter, E Collis, W Barendse, R Hawken

10.45 -11.00 - O2 - Comparative Bioinformatic Analysis of the Transcriptional Response to Salmonella Enterica Serovar Choleraesuis Suggests Novel Targets of Nfκb are Activated in the Porcine Mesenteric Lymph Node -
CK Tuggle, Y Wang, OP Couture, C Christian, L Qu, JJ Uthe, SMD Bearson, D Kuhar, JK Lunney, D Nettleton, JCM Dekkers

11.00 – 11.15 - O3 - Tissue-specific expression analysis of alternative splicing in the pig -
A-B Nygard, S Cirera, M Gilchrist, J Gorodkin, C Jørgensen, M Fredholm

11.15 – 11.30 - O4 - Proteome Analysis of Bovine Myogenesis Gives New Leads to Optimize Meat Quality and Muscle Growth Efficiency -
T Chaze, B Meunier, C Chambon, C Jurie, B Picard

Session 8: “Animal Genomics in Industry”                
Chairperson: Chris Warkup (Genesis-Faraday, UK) & Dr Anne-Marie Neeteson-van Nieuwenhoven (EFFAB/European forum of farm animal breeders)

• Genomic Selections: Evolution or Revolution? - Dr Wiepk Voskamp (HG, The Netherlands)
• The Use of Genomics Information in Poultry Breeding Programs – A Global Breeder’s View - Dr Santiago Avendano (Aviagen, UK)

Session 9: “Open Session 2”
Chairs: Liz Glass (Roslin Institute) and Sue Sipkovsky (Michigan State University)

13.45 – 14.00 - O5 - Accuracy of Genomic Breeding Value Prediction Using Different Models
M Calus, T Meuwissen, S De Roos, R Veerkamp

14.00 - 14.15 - O6 - Genome-Wide Expression Consequences of a Disease Resistance QTL are Strongly Influenced by the Genetic Background
H Noyes, M Agaba, S Anderson, A Archibald, A Brass, J Gibson, L Hall, H Hulme, S Kemp

14.15 - 14.30 - 07 - Gene Expression and Immune Studies in Bos Taurus and Bos Indicus Cattle Infested with Rhipicedphalus Microplus
LA Jackson, EK Piper, ME Jones, AE Lew, C Gondro, PM Moolhuijzen, NN Jonsson

14.30 - 14.45 - O8 - A Phylogenetic Approach To Identify Substitutions Of Functional Relevance In Bovine Toll-Like Receptor 2
OC Jann (Roslin Institute, United Kingdom),
D Werling, EJ Glass

Session 10: “Systems Biology”
Chairperson: Dr Dave Burt (Roslin Institute) & Prof Alan Archibald (Roslin Institute

• From Bioinformatics to Systems Biology and Beyond - Prof Igor Goryanin (University of Edinburgh)
• Cap-Analysis Gene Expression (CAGE) Analysis of Transcriptional Complexity and Regulation - Dr Piero Carninci (RIKEN, Japan)